Ethnic differences in genetic predisposition to hypertension
نویسندگان
چکیده
منابع مشابه
A genetic predisposition to hypertension?
Hypertension is a major public health problem, and yet, the molecular mechanisms underlying hypertension are poorly understood in the majority of patients. A complex disorder, both environmental and genetic factors predispose individuals to hypertension. Whereas we know much about environmental factors, such as salt intake and exercise, that affect blood pressure, we know less about genetic fac...
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The purpose of this study is to evaluate the relationship between aldosterone and blood pressure in a total of 220 normotensive and 293 essential hypertensive subjects in 2 genetically distinct populations-blacks and white French Canadians. The 24-hour blood pressure monitoring was performed under standardized conditions after discontinuing antihypertensive medications. Plasma renin activity an...
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The genetics of asthma and atopy is complex, but can be approached by studies of both candidate genes and mapping of susceptibility loci. Genetic factors conferring susceptibility to disease may vary among ethnic groups. We present our experience with some candidate gene studies for asthma and atopy and susceptibility locus mapping for linkage to chromosome 5q.
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The genetic component appears to be inherited in an autosomal dominant fashion. This means that each child has a 50% chance of inheriting. The genetic variant(s) can be inherited from either the father or the mother, and can be passed along to both sons and daughters. Current understanding of the pathogenesis of the syndrome suggests, that it is a complex multigenic disorder (a genetic problem ...
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ژورنال
عنوان ژورنال: Hypertension Research
سال: 2012
ISSN: 0916-9636,1348-4214
DOI: 10.1038/hr.2012.44